Thursday 11 October 2012

Peptide Synthesis

As most of the biologically proteins which are active and those are about 150 residues in length, though, it has been revealed that the majority of activities is kept within 100 residues.
Majority of commercial proteins are made by recombinant methods, whereby genes coding for specific sequences of peptide are inserted into a host organism, for synthesis in bulk. While the endotoxin contamination can be problematic for recombinant methods, chemical synthesis offers much cleaner products.      
We provide custom peptide and build up a proprietary synthesis strategy that lets the synthesis of peptides equal to around 120 residues-with speed and purity, usually only feasible with shorter fragments of peptides.

As most biologically those are active proteins which are around 150 residues in length, though, it has been observed that most of the activity is reserved inside 100 residues. Most proteins which are commercial are prepared by recombinant methods, whereby genes coding for specific peptide series are inserted into a host organism, for mass synthesis. At the same time as the endotoxin contamination can be difficult for those ways which are recombinant, syntheses which are chemical offers much cleaner products.     

Typical Peptide Synthesis

Our typical peptide synthesis is intended for a peptide along with average complexity. There is also available synthesis as follows:
1.    Extended peptide synthesis
2.    Alteration of peptide
3.    Library of peptide
4.    Area of nucleic acid synthesis
5.    Bioconjugation
6.    Transporter conjugations


We have good experience in synthesizing so many custom peptides, as most of them are large peptides. This rising sector of large peptide synthesis always uses peptides or peptide resembling compounds for pharmaceutical drug finding. Though, the tough challenge of long peptide synthesis is to prevail over the huge increasing result of the yield. Insufficiencies which are synthetic connected with peptide aggregation, like a sluggish or incomplete coupling or deprotection reactions, exemplify the intricacy that often arises.       

We have developed a solid-phase synthesis technology which beats these restrictions, achieving syntheses of long proteins entirely by some methods which are chemical. Our expert panel examines your favorite protein and will review possibility to make the most of the success of the synthesis from large and complicated peptides.   

For more information on Bioconjugation, Peptide, Custom Peptide, Please Visit: Peptide Synthesis   


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